ZitatTYNE, England, March 17, 2017 (LifeSiteNews) – The United Kingdom's Human Fertilisation and Embryo Authority has granted Newcastle University permission to begin creating human embryos who have three parents.
The chair of the Human Fertilisation and Embryo Authority, Sally Cheshire, confirmed Thursday that "the HFEA has approved the first application by Newcastle Fertility at Life for the use of mitochondrial donation to treat patients."
The UK first approved three-parent embryos in 2015. This will be the first time scientists will carry out the procedure, which involves killing human embryos to manufacture another.
The purpose of creating embryos this way is to attempt to modify them to not have certain genetic diseases. But bioethicists say this technique involves a multitude of ethical and moral problems.
The embryos will have DNA from two mothers and one father, Dr. David A. Prentice, vice president and director of research at the Charlotte Lozier Institute, told LifeSiteNews. A small part of the mother's DNA will be replaced with DNA from another woman. This is done in the hopes of preventing the main mother (for lack of a better phrase) from transferring genetic diseases to the child.
"The type of technique they’re using actually involves destroying two embryos to then re-combine [their] parts for a third constructed embryo with genetics from two women and one man," said Prentice. "This technique starts with death of young human embryos."
While the technology is incredible we ought to be very careful when applying it to DNA not only for moral reasons but also for scientific ones. Considerinting the fact that as DNA is studied more and more it is revealed to be incredibly complex and likely contains many as yet unexplored levels of functionality.
Here is a very general overview
Back in 1953 wen Watson and Cricks first announced the discovery of the now famous double double helix it was believed that th4re was a one to one relationship of genes to inherited characteristics.
Ii was once gospel that while environmental and lifestyle factors could influence how a genetic trait was expressed no changes were passed on to future generations. I remember thinking how wonderful. Swap out the defective gene for a chronic condition e.g. diabetes, for a good gene. Over time it became evident That it would not be so simple.
What was once referred to a s junk DNA has held some surprises. Study of 'Junk ' or non-coding DNA continues to divulge more and more surprises.
Some Examples: 'Junk DNA' can sense viral infection: Promising tool in the battle between pathogen and host April 24, 2012 Source: American Friends of Tel Aviv University
Summary: Non-coding RNA -- molecules that do not translate into proteins -- were once considered unimportant "junk DNA" by researchers. Now researchers have discovered that when infected with a virus, ncRNA gives off signals that indicate the presence of an infectious agent, providing researchers with a new avenue to fight off infections. ............................................................... https://www.sciencedaily.com/releases/20...20424142253.htm
Epigenomes An epigenome consists of a record of the chemical changes to the DNA and histone proteins of an organism; these changes can be passed down to an organism's offspring via transgenerational epigenetic inheritance. Changes to the epigenome can result in changes to the structure of chromatin and changes to the function of the genome.[1]
The epigenome is involved in regulating gene expression, development, tissue differentiation, and suppression of transposable elements. Unlike the underlying genome which is largely static within an individual, the epigenome can be dynamically altered by environmental conditions.[2] https://en.wikipedia.org/wiki/Epigenome
Darwin's finches and epigenomes:
Darwin's Finches: Answers From Epigenetics by Jeffrey P. Tomkins, Ph.D. * Resources › Life Sciences Resources › Genetics
Authentic speciation is a process whereby organisms diversify within the boundaries of their gene pools, and this can result in variants with specific ecological adaptability. While it was once thought that this process was strictly facilitated by DNA sequence variability, Darwin's classic example of speciation in finches now includes a surprisingly strong epigenetic component as well.1
Epigenetic changes involve the addition of chemical tags in an organism's genome without actually changing the genetic code. Both the DNA nucleotides and the proteins that DNA is wrapped around (called histones) can be chemically tagged by different types of controlling molecules that determine how genes are turned on and off. Thus, the epigenetic regulation of the genome can produce differences in traits without actually being related to changes in the DNA sequence itself. What's even more amazing is that these changes can be inherited over multiple generations. Thus, epigenetic changes unexpectedly facilitate variability and speciation within created kinds.